Hamdard Safi Uses, Benefits and Cautions

Know the ingredients and uses of Hamdard Safi . Know the diseases in which this medicine is effective. This is very effective in skin problems. Learn how to use this medicine.

Hamdard Safi is a herbal Unani medicine. It is prepared from 28 medicinal herbs including Senna, Revand Chini, Neem, Chiraita, Daru Haldi, Haritaki, Nishoth, Giloy and Tulsi.

It is bitter in taste and helps to remove toxins from the blood. Hamdard’s Safi purifies the blood and removes acne, blackheads and skin blemishes. It makes the skin soft, smooth and glowing. When taken continuously for one month it shows good results. It keeps constipation away and supports better digestion. It also helps in weight loss.

Here is given more about this medicine, such as benefits, indication/therapeutic uses, composition, and dosage.

About Unani

Unani System of medicine evolved in Greece and was first introduced to India by the Arabs. It is also called as Greco-Arab medicine, Unani Tibb, Arabian medicine, or Islamic medicine. Hippocrates is known as the father of this system of medicine. The theoretical framework of Unani medicine is based on his teachings.

It is a traditional medicinal system and commonly practiced in South Asia. The origins of Unani medicines are found in the doctrines of the ancient Greek physicians Hippocrates and Galen. It was later developed and refined through systematic experiment by the Arabs. Unani medicines are prepared from medicinal plants, minerals, animals products, etc. In Unani medicine, single drugs or their combinations in raw forms are preferred over compound formulations. The naturally occurring drugs used in this system are usually free from any side effects.

  • Type of medicine: Proprietary Unani Medicine
  • Manufacturer: Hamdard Laboratories (India) established by Late Hakeem Abdul Hameed Sahib.
  • Purpose: Blood purification
  • Safi Syrup MRP / Price: Rs. 80.00 for 200 ml, Rs. 190.00 for 500 ml
  • Availability: In India, Pakistan and Bangladesh at pharmacy Stores and online.
  • Suitable for: Both males and females
  • Taste: Bitter
  • Pacifies: Pitta, and Kapha

Medicinal Properties of Hamdard’s Safi

  1. Anthelmintic: Expel parasitic worms (helminths) and other internal parasites from the body.
  2. Antiinflammatory: Reducing inflammation by acting on body mechanisms.
  3. Antioxidant: Neutralize the oxidant effect of free radicals and other substances.
  4. Antibacterial: Active against bacteria.
  5. Antiviral: Effective against viruses.
  6. Carminative: Preventing the formation or causing the expulsion of flatulence.
  7. Diuretic: Promoting excretion of urine/agent that increases the amount of urine excreted.
  8. Depurative: Purifying agent.
  9. Detoxifying: remove toxic substances.
  10. Digestive: Digestant.
  11. Purgative: laxative in effect.

Ingredients of Hamdard Safi

Each 5 ml (One teaspoonful) contains aqueous extract of:

  1. Senna 160.45 mg
  2. Turbud 25.45 mg
  3. Gulab ke phool गुलाब के फूल 24.77 mg
  4. Burada Sheesham 13.4 mg
  5. Safed chandan 11.36 mg
  6. Giloy 14.09 mg
  7. Haritaki 22.04 mg
  8. Narkachur 11.36 mg
  9. Chiraita 17.38 mg
  10. Burge Kasundi 13.40 mg
  11. Mundi 15.45 mg
  12. Neelkanthi 16.13 mg
  13. Shahtara 22.72 mg
  14. Kachnaar 15.45 mg
  15. Neem bark 19.43 mg
  16. Burge Tulsi 13.4 mg
  17. Zarambaad 11.36 mg
  18. Daru Haldi 9.43 mg
  19. ChobChini 11.36 mg
  20. Post Keekar Bark 42.84 mg
  21. Sankhaahuli 14.09 mg
  22. Sarfooka 18.06 mg
  23. Ushba 5.68 mg
  24. Brahmi 9.09 mg
  25. Chakshu 9.09mg
  26. Bekh Kaasni 9.09 mg
  27. Unaab 11.36 mg
  28. Revand Cheeni 22.72 mg
  29. Qand Sadaid q.s (to make 5 ml)
  30. Shora Desi 227.27 mg
  31. Milleh Firangi 1.25 g

Key Ingredients

Senna (Cassia angustifolia Vahl, Cassia senna Linn var. senna.) is bitter purgative. It is used in combination with other warming herbs to protect the digestive fire and to clear ama.

Ama is formed in the body due to incomplete digestion of foods. It is cold, slimy and heavy. This toxic poisonous waste produced by digestive weakness is said to clog the channels in the body (the shrotas), giving rise to disease. Ama is first localized to Kapha regions (chest, stomach, joint) and then vitiated by Vata, Pitta, and Kapha and circulates in the whole body.

Senna has Carminative, Expectorant, Hepatoprotective, Peristaltic and laxative action.

Senna has few side-effects. It is a habit forming laxative. It should not be used (contraindicated in) in lactation, pregnancy, presence of intestinal obstruction, acute inflammatory intestinal diseases, appendicitis and with children under 12 years old. Its chronic use or abuse can cause losses of electrolytes,in particular potassium ions, resulting inalbuminuria, haematuria and inhibition of intestinalmotility. Potassium loss may potentiatecardiac glucosides and have an effect on antiarrhythmic medication.

Also Read: Herb information Senna or Sanai

Turbud / Nisoth / Opercullna (Operculina turpethum, Synonym Ipomoea turpethum R. Br.) is also a mild laxative that treats constipation. It is a traditionally used to treat skin diseases, sores, boils, itches, diarrhea, piles, dyspepsia, rheumatism, gout, vomiting, biliousness, urinary diseases such as strangury, dysuria, stones in the bladder, diseases of the spleen and all ailments due to excessive indulgence in alcohol.

Also Read: Nishoth Information, Medicinal Uses and Side-effects

Haritaki / Harad / Halelaa siyaah or Chebulic Myrobalan, is used in the treatment of for the digestive weakness, oedema, dermatosis, urinary diseases, irregular fever and as a blood purifier. It has laxative activity. Haritaki should not be taken in acute coughs, acute diarrhea, and early stage dysentery.

Sheesham (Dalbertgia sissoo), is used to treat leprosy, boils, eruptions and to allay vomiting. It is considered Cold (2 degree) and dry (2 degree) in Unani and has alterative properties.

Neem (Azadirachta indica, family Meliaceae), is also known as Margosa, Nim, Nimba, Nimbatiktam, Arishtha, Praneem. The Neem bark is cool, bitter, astringent, acrid and refrigerant. Bark of the tree is useful in intestinal worms, heat-rash, boils, wounds, jaundice, leprosy, skin disorders, stomach ulcers, chicken pox, malarial fever, tiredness, cough, fever, loss of appetite, worm infestation, etc. It heals wounds and vitiated conditions of kapha, vomiting, skin diseases, excessive thirst, and diabetes.

The bark of the tree is used in Ayurveda for the treatment of the skin diseases, excessive pitta, excessive Kapha, toxins in the body, bleeding disorders and healing of wounds.

In Unani, Neem is considered Hot and Dry (both 2nd degree).

Babool (Acacia arabica) is used for the skin diseases and as an anthelmintic. It has strong astringent action and is used to contract and strengthen mucus membranes throughout the body.

In Unani, its Mizaj (Temperament) is Cold and Dry (both 2nd degree).

Giloy (Tinospora cordifolia), is a climbing deciduous shrub belonging to the family Menispermaceae, found throughout India. It is also known as Guduchi, Amrita, Amritavalli, Madhuparni, Guduchika, Chinnobhava, Vatsadani, Tantrika, Kundalini, Chakralakshanika (Sanskrit), Gurcha (Hindi), Garo, Galac (Gujarati), Thippateega (Telugu),Amrita, Gilo (Kashmiri), Chittamrutu (Malayalam), Guluchi (Oriya), Gilo (Punjabi), Seendal, Seendil Kodi (Tamil), Siddhilata, Amarlata (Assamese). It is one of the most important medicinal plant and the forms an important drug of the Ayurvedic system of Medicine. It is a Rasayana herb and used to treat for many diseases such as general debility, fever, diabetes, dyspepsia, urinary infections, jaundice, burning sensation, fever, edema and skin diseases.

It has adaptogen, immunostimulant, antioxidant, anticancer and antidiabetic properties.

Benefits of Hamdard Safi

  1. It is a herbal medicine.
  2. It works on the basic reason for any skin diseases i.e. toxins in blood. When the reasons is cured the problem is get solved.
  3. It gives relief in constipation due to the presence of Senna.
  4. It removes toxins from the blood due to its bitter ingredients.
  5. It supports proper functioning of the liver, thyroid, and other important body organs.
  6. It improves blood circulation due to the presence of Tulsi.
  7. It purifies the blood.
  8. It keeps skin blemish free.
  9. It prevents pimples and acne outbreak.
  10. It improves the complexion and makes the skin radiant.
  11. It has diuretic properties and causes weight loss.
  12. It pacifies aggravated Pitta inside the body and hence gives relief in rashes, boils and nose bleed which occur due to excess heat in the body.

Important Therapeutic Uses of Hamdard Safi

Safi herbal extract keeps skin pimple free and glowing. The ingredients present in this medicine supports proper functioning of the digestive and excretory system. If you are taking Hamdard Safi regularly for period of time (1-2 months or till the skin diseases are cured) then it is an effective pimple fighter and makes your skin radiant naturally.

  1. Acne vulgaris (chronic skin disease occurring when hair follicles become clogged with dead skin cells and oil from the skin)
  2. Blood disorders
  3. Boils (painful bump under the skin)
  4. Constipation (difficulty in emptying the bowels, usually associated with hardened faeces)
  5. Dark spots, hyperpigmentation
  6. Dulling of complexion over the time
  7. Dermatitis (condition in which the skin becomes red, swollen, and sore, sometimes with small blisters)
  8. Epistaxis / nose bleed / nakseer (bleeding from the nose)
  9. Indigestion
  10. Itching
  11. Pimples, acne, blemishes
  12. Skin problems
  13. Skin eruptions
  14. Urticaria, skin rashes

The Dosage of Hamdard Safi

  1. Regular intake of Hamdard Safi for 3-4 weeks effectively treats various skin diseases that occur due to toxins in the blood.
  2. Use Hamdard Safi as per uses direction and for period of time.
  3. How to Take Safi: 10 ml (2 teaspoonful) once a day with one glass of water at breakfast.
  4. Children (>12 years) may take 1 teaspoonful at breakfast.
  5. While on treatment, avoid fried, spicy and rich food. Have easily digestible light foods.
  6. Safi medicine is very bitter.
  7. Shake the medicine well before use.
  8. Keep in cool and dark place.

Side effects

  1. Do not use in pregnancy and lactation.
  2. Do not use Hamdard Safi in diarrhea as it is has laxative action.
  3. It may increase frequency of urination.
  4. It can cause weight loss.


  1. Hi i want to know can SAFI cause haemorrhoids or if not is safi is good in haemorrhoid or it is effective to help to prevent?

  2. Plz suggest something for uric acid I have been struggling with it for a long time.

  3. Plz suggest something for uric acid ? I’ve been struggling with it for a while .

  4. Can I take Safi at morning before workout?

  5. can you take safi with cholesterol medication

  6. Eng.Ahmed Qalib Ismail

    I have hay fever and my nose are blocked or stuffed-up nose at night both of them, I have a runny nose and itchiness.I think this caused for allergic. my question is can I use SAFI for treatment?

  7. pls do safi reduce fat and weight,because i bought it purpose to reduce my weight

  8. i have vaginnal infection take zentro flagyl a month but not good my friend suggest for safi for allergy and said dont use any antibacterial or fungal cream can i take safi its my last hope

  9. I don’t want a weight loss, i am taking safe for skin treatment shall i continue

  10. Pijush Kanti Dey

    I want not to loss my weight because I’m very thin. So how to use safi? how to use safi without weight loss?

  11. I am taking safi without diluting in water first i m taking 2 teaspoon of safi and then i m drinking water….is this cause any side effect

  12. I have startedtaking safi from past 1 n half month it really improved my skin but there r still some acne breakouts n scars what shall I do n also for skin pores

  13. I took safi ( 2 teaspoon in a cup of water)in the morning before breakfast everyday for 21 days. The side effect that I experience is going to the bathroom twice or thrice a day( diarrohoea type). Is it due to safi?

  14. Is it helpful in etching in some parts of my body….??

  15. i am having a boil under my arm every 15 days which pains a lot will safi helps for this

  16. i want t begin with safi . i want to know strictly what can i eat and wt not..also i have dry skin will this product create more dryness as other acne emoving face wash do?

  17. Hi. I want to treat constipation using safi. So please tell me. When should I take safi.. Before or after meals, early in the morning or before going to sleep.. AND if I dilute it with water will it help in treating constipation

  18. for how long i have to wait for next meal after taking safi ?

  19. Diabetic patient can have safe or not?

  20. Can I use saafi for pcos or irregular periods

  21. I have a big problem of pimple and acne…and it makes a dark spot on my face…in that case can I use safi to make it clear? this pimples creates some holes in my cheeks small in size…so can safi fill that holes?

  22. Can we drink safi in summers season

  23. I test my blood and my ESR is 65mm/ hrs. Can i use Safi for controll my ESR ? Rply plz md’m

  24. mayuri udapurkar

    when i eat any thing having tamarind the pimples increase. what to do?

  25. I have an oily and acne prone skin, I have just started taking safi..How Should I take it fr effectv results? Before meals?

  26. What is the side effect of too much consumption of safi??

    • It may cause arsenic poisoning(so dilute 2 spoon it in 1 glass water), it may cause loose motion and stomach upset and many others.

  27. hi…in these summer….i got so many pimples first time…n they are leaving black spots…..should i take safi?

  28. Can we take it when stomack is empty?

  29. I have light pigmentation near by mouth. Do saafi will help me??

  30. I m 44 Years Old and using saafi for last 2 months for constipation, as i stop taking saafi, i got constipated but on regular use, i feel Ok, what should i do?? and also, i got very painful pimple in nose and eye occasionally. For how long should i use Saafi.

  31. Iam slim so if i take safi it will lose my weight??

  32. instead of mixing two teaspoons of safi with water, can’t we first have the syrup and then quickly have warm water after it?

  33. My 3 years old child suffer from hives for last 1 month… Can I give safi for him

  34. Is it safe to take safi above 60 age. Any age limits for this?

  35. How to take safi with water?
    Can we mix both(water&safi)with eachother

  36. I drank safi blood purifier meticulously for a month. My prognosis about this particular product is that it might not work for anyone or everyone. I personally didn’t find any effects. I wasn’t expecting to do wonders from day one. But I didn’t have even the slightest benefit from it. During the course, I exercised regularly, on strict diet avoiding oily or fried foods. I used to have exactly the same way as prescribed on the bottle and what Ms. Anupama is preaching here. With all due respect to her, I find this product an utter waste. This is my personal experience and opinion, so one shouldn’t be offended by what I have mentioned here. Anyone who suffers from skin ailments or any other ailments, I would rather suggest a good medical practitioner. All the best!!

  37. M having safi from about 2 days……so pls explain me what to eat and what not to eat while having or after having safi……..and can i go out after having safi……is there sunlight effect

    • avoid oily and spicy stuffs. Otherwise not restriction but make sure you are taking it by adding it in 200 ml water otherwise will harm you.

  38. please tell me cautions for this.which one things i must not take during safi process.

  39. My skin is dark shall I take safi , and I dnt have any pimples and spots on my face.

  40. Can we take safi in perides

  41. Can Safi be used for psoriasis. Thanks.

  42. Can we take safi , even if we smoke and drink alcohol?

  43. I don’t know what happens but, whenever I drink it within 2-3 hours it would start itching randomly on body creating red rashes. Any explanation??

  44. I have been suffering from chronic urticaria for a year now.. Does safi help? If yes what is the dosage and duration to be taken? Any food habits recommended? I am a Non vegeterian.

  45. I am suffering from tescle cronic orcitis prob. So left side testicle bigger then right side. As it is viral can i get remedy from Safi? I am 28 years old married

  46. I have regularly used Safi for 2 months but didn’t see much difference in my skin.
    I was using this to cure to my pimples and acne i regularly get on my forehead.
    Should i continue drinking this or take a break for sometime? Pls suggest

  47. I am a breast feeding mother n my baby is ten months old…. Can I take this safi

  48. I was drinking Safi..and im 1 month pregnant,so i stop taking it.is my baby safe

  49. When do WE have to take safi afer breakfast or befoer…..

  50. Impossible ….how can it contain arsenic. .. It is a poisonous element

    • In Ayurveda and Unani many medicine contains elements like mercury, arsenic, sulpher, tin etc by doing purification.
      Safi has very small amount of arsenic that’s why it must be diluted in a glass of water before drinking to avoid arsenic poisoning.

    • In Ayurveda all medicines whose names contains word “Ras” are metal based but those are prescription medicines.

  51. If safi contains arsenic then why is it selling in the market? I checked the reviews online but no one has experienced any harmful side effects. So is it safe to take?

  52. Can we use safi to get periods ?

  53. can we use it while breastfeeding? As i am suffering from lot of constipation and skin itching problems. I am feeding 4th month boy.

    • No, do not take safi as it contains arsenic, for constipestion drink 3 litre water daily and walk at-least 30~45 minutes and eat some salad regularly.

  54. I m taking safi from last 1 month for my acne and pimple but dint notice much difference i think my spot looks more should i continue and keep patince or leave plss advise.

  55. Can we use it .. while periods ??

  56. I have dry itchy scalp and Dandruff problem. And i have gas and bloating. Is it safi useful to this problems???

  57. I m constipating even after taking safi… i m even taking haritaki at night is that k ?

    • Drink atleast 3-4 litre water daily and do walk for 45 daily. Eat kishmish in evening a handful.
      Do this daily and tell me result after 7 days.

  58. I am going to start with this tonic,but i have oily skin and have lots of pimples and acne,can it be used by the people having oily skin.is it effective to all types of skins???

  59. can safi reduced the high uric acid level?

  60. I’ve been drinking Safi twice a day, two spoonful both the times. I’m experiencing good skin results but I think I’m getting fat. Also, my diet contains spicy food, is that the problem here?

  61. Kya ladke bhi use kar sakte he ,?? Aur kuch side effects to nahi honge na use kiya to

  62. is there a problem if we use safi regurarly ??
    like … I have been using it since 4 yrs and the results are pretty good …. but I don’t gain weight lol…. what to do ?

    • You should take break of 15~30 days after 3-4 months. No problem until you are taking safely mean diluting this syrup in 250 ml water as this contains arsenic.
      As this contains arsenic, you shouldn’t take this unnecessarily.

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.