Yasmin (28) is a daily regular oral hormonal contraceptive pill (drospirenone/ethinyl estradiol) used to prevent pregnancy. Yasmin contains two female hormones, synthetic estrogen called ethinyl estradiol and progestin called drospirenone.
It is available in a pack of 28 pills. It does not allow pregnancy by preventing ovulation, implantation and making cervical secretions thick. It is supposed to be 99% effective when taken correctly.
Here is given more about this medicine, such as benefits, indication/therapeutic uses, composition and dosage.
- Category: Hormonal Combined birth control pill
- Contains: Progestin and estrogen
- Pack: 28 tabs
Ingredients of Yasmin
Yasmin (drospirenone/ethinyl estradiol) tablets are available in blister packs.
Each blister pack contains 28 film-coated, round, bi-convex tablets in the following order:
21 yellow tablets each containing 3 mg drospirenone and 0.03 mg ethinyl estradiol embossed with a “DO” in a regular hexagon on one side.
7 inert white tablets embossed with a “DP” in a regular hexagon on one side.
Drospirenone is a synthetic progestational compound and has a molecular weight of 366.5 and a molecular formula of C24H30O3.
Ethinyl estradiol is a synthetic estrogenic compound and has a molecular weight of 296.4 and a molecular formula of C20H24O2.
The inactive ingredients in the yellow tablets are lactose monohydrate NF, corn starch NF, pregelatinized starch NF, povidone 25000 NF, Magnesium stearate NF, hypromellose USP, macrogol 6000 NF, titanium dioxide USP, talc USP, and ferric oxide pigment, yellow NF. The white inert film-coated tablets contain lactose monohydrate NF, corn starch NF, povidone 25000 NF, magnesium stearate NF, hypromellose USP, talc USP, and titanium dioxide USP.
Indications of Yasmin
It is used to prevent pregnancy in woman.
Yasmin lowers the risk of becoming pregnant primarily by suppressing ovulation. Other possible mechanisms may include cervical mucus changes that inhibit sperm penetration and endometrial changes that reduce the likelihood of implantation.
Dose and Administration
- Take one tablet by mouth at the same time every day.
- The failure rate may increase when pills are missed or taken incorrectly.
- Take as directed on blister pack.
- Single missed pills should be taken as soon as remembered.
How to Start Yasmin
- It is better to start Yasmin from first day of menstrual period.
- Take one Yasmin pill daily for 21 consecutive days.
- This is followed by one white tablet daily 22nd day through 28th day.
Some Important Points to be remembered
- It should be taken in the order directed on the package at the same time each day.
- It is better to take it after the evening meal or at bedtime with some liquid.
- In case of severe vomiting or diarrhea, absorption may not be complete and additional contraceptive measures should be taken.
- If vomiting occurs within 3-4 hours after tablet-taking, this can be regarded as a missed tablet.
- If you miss pills you could get pregnant. This includes starting the pack late. The more pills you miss, the more likely you are to get pregnant.
- As progestin drospirenone may increase potassium level, it should not be used in kidney, liver or adrenal disease because this could cause serious heart and health problems.
- You may have spotting or light Bleeding at unexpected times, or may feel sick to their stomach during the first 1-3 packs of pills.
- Missing pills can also cause spotting or light bleeding, even when you make up these missed pills.
- Intake of 2 pills gives feeling of sickness.
- Use Before or During Early Pregnancy
- Extensive studies have revealed no increased risk of birth defects in women who have used oral contraceptives prior to pregnancy.
- Studies also do not suggest a teratogenic effect when taken inadvertently during early pregnancy, particularly in so far as cardiac anomalies and limb-reduction defects are concerned.
Adverse Reactions / Side Effects
- Serious cardiovascular events and stroke
- Vascular events
- Liver disease
- Irregular uterine bleeding
- Breast tenderness
- Spotting or bleeding between menstrual periods
- Acne, low libido, fluid retention, blotchy darkening of the skin, especially on the face
- High sugar, fat (cholesterol, triglyceride levels) in blood
- Problems tolerating contact lenses
- Weight changes
There have been no reports of serious ill effects from overdose, including ingestion by children. Over dosage may cause withdrawal bleeding in females and nausea.
- Yasmin should not be used in following medical conditions:
- Renal impairment
- Adrenal insufficiency
- High risk of arterial or venous thrombotic diseases
- Blood clots in legs (deep vein thrombosis), lungs (pulmonary embolism), or eyes (retinal thrombosis)
- Stroke, heart attack, heart valve problems, heart rhythm abnormalities, high blood pressure
- Diabetes with kidney, eye, nerve, or blood vessel damage
- Liver, kidney or adrenal disease
- If you ever had Jaundice caused by pregnancy
It should not be prescribed to women, in case:
- If age over 35
- Women who smoke
- Pregnant woman
- Deep vein thrombosis or pulmonary embolism
- Cerebrovascular disease
- Coronary artery disease, thrombogenic valvular or thrombogenic rhythm diseases of the heart
- Inherited or acquired hypercoagulopathies
- Uncontrolled hypertension
- Diabetes mellitus with vascular disease
- Headaches with focal neurological symptoms
- Migraine headaches with or without aura
- Undiagnosed abnormal uterine bleeding
- Breast cancer or other estrogen v n- or progestin-sensitive cancer, now or in the past
- Liver tumor (benign or malignant) or liver disease
- Certain other medical conditions
- Stop Yasmin in case of arterial or venous thrombotic event