Laxirid from Dabur India Limited, is an ayurvedic medicine for Constipation. It gives symptomatic relief from constipation. Laxirid is available in form of syrup and tablets.
The composition of Laxirid tablet and syrup is completely different. In tablets, the main ingredient is Senna which is a habit-forming laxative. Senna is a natural laxative made from the leaves and fruit of the Senna plant. Senna contains many chemicals called sennosides. Sennosides acts as a stimulant laxative and works by irritating and stimulating intestinal cells. This produces contractions in intestines, water influx to the intestines and bowel movement.
The Laxirid syrup contains Operculina turpethum as the main ingredient. Operculina turpethum, is known as Trivrut, Nishoth or Indian Jalap. The root is used traditionally as a laxative or purgative. It works as laxative by enhancing retention of intestinal fluid by hydrophilic or osmotic mechanism and stimulation of intestinal motility.
Laxirid is effective in the management of Functional Constipation. Here is given more about this medicine, such as benefits, indication/therapeutic uses, composition and dosage.
- Manufacturer: Dabur India Limited
- Availability: Online and at medical stores
- Type of medicine: Proprietary
- Main Indication: Constipation
- Dabur Laxirid Syrup Syrup 200 ml @ INR 110
- Dabur Laxirid Laxirid 60 Tabs @ INR 150.00.
Dabur Laxirid Composition
Ingredients present in this formulation are given below:
Each Dabur Laxirid film coated tablet is prepared from:
- Svarnapatri (Cassia angustifolia, lf., Ext)- 180mg
- Yavani (Trachyspermum ammi, fr., Oil) – 30mg
- Colours Quinoline yellow, Tartrazine, Titanium dioxide
- Permitted Excipients: QS
- Preservative: Sodium Methyl Paraben IP
- Sodium Propyl Paraben IP
Each 5 ml of Dabur Laxirid Syrup Syrup is prepared from:
Extract derived from
- Trivrit (Operculina turpethum, Root) 3.50 gram
- Yashti (Glycyyrrhiza glabra, Root) ),50 gram
- Flavoured Syrup Base QS
- Preservative: Sodium Methyl Paraben IP
- Potassium sorbate IP
- Sodium benzoate IP
Key Ingredients of Dabur Laxirid
Cassia angustifolia (Cassia lanceolata Wall., Cassia elongata Lem—Lisanc., Cassia medicinatis Bisch., Senna officinalis Roxb., Senna angustifolia Batka) is Latin name of Senna.
Senna contains a glucoside acid called cathartic acid, chrysoretin a yellow colouring matter, a peculiar non-fermentable saccharine crystalline principle termed cathartomannite and two bitter principles sennacrol and sennapicrin. Senna leaf and fruit are stimulant laxatives, where the leaf is a stronger cathartic than the fruit.
Senna has following Ayurvedic properties
- Rasa (taste on tongue): Kashaya (Astringent), Katu (Pungent), Tikta (Bitter)
- Guna (Pharmacological Action): Laghu (Light), Tikshna (Sharp), Ruksha (Dry)
- Virya: Ushna (Heating)
- Vipaka (transformed state after digestion): Katu (Pungent)
- Karma: Rechana / laxative
Senna has few side-effects. It is a habit-forming laxative. It should not be given to children under 12 years old. It is used in combination with other warming herbs to protect the digestive fire and to clear Ama. It has Carminative, Expectorant, Hepatoprotective, Peristaltic and laxative action.
Trivrt is also known as Turpeth, Nishoth and Indian Jalap. It is used in Ayurveda for treatment of constipation, digestive ailments, fever, anemia, intestinal parasites etc. The powdered root is given as a purgative. The use of root powder gives relief in habitual constipation, colic and piles.
Operculina turpethum roots contain the glycosidic resin (about 10%), turpethin andh turpethein. Turpethein is made up of 1-turpethein containing jalapic, ipomoic and tampicolic acids and f-turpenthein. It gives laxative action to the drug.
Operculina turpethum is Abortifacient or Induces abortion.
Operculina turpethum should not be used (Contraindicated) in pregnancy, in children below 12 years of age, in elderly, in physically or mentally weaker persons, and in persons suffering from diarrhea, bleeding per rectum, rectal prolapse, or fecal incontinence.
Large doses may lead to serious complications such as loose motions, bleeding per rectum, vomiting, abdominal pain, chest pain, dehydration, hypotension, vertigo, confusion, shock, and unconsciousness.
Trivrt also increases Vata in body and hence excess intake of this medicine may cause bloating, flatulence and pain.
Ayurvedic Action / Karma of Dabur Laxirid
- Anulomana: laxative, redirects the flow downwards.
- Deepana: Appetiser
- Pachana: Toxin digester
- Rasayana: Rejuvenative
- Virechana: Medium strength laxative.
Biomedical Action of Dabur Laxirid
- Carminative: Preventing the formation or causing the expulsion of flatulence.
- Laxative: Tending to stimulate or facilitate evacuation of the bowels.
Dabur Laxirid Health Benefits
- It relieves constipation.
- It alternative to chemical laxatives.
- It helps regulate bowel movements.
Dabur Laxirid Therapeutic Uses
- Laxirid gives symptomatic relief from constipation.
- Chronic constipation
- Constipation associated with other medical condition
Dabur Laxirid Dosage
The recommended dosage of medicine is 1-2 tablets.
- The syrup is taken in dose of 1-2 teaspoonful (5-10 ml) once a day.
- Children above the age of 12 can be given, 2.5ml to 5ml, once a day.
- It should be once a day only, at bed time.
- It is to be taken with water.
- Or take as directed by doctor.
Contraindications of Dabur Laxirid
- Intestinal obstruction
- Abdominal pain of unknown origin
- Intestinal inflammation
- Prolapsed rectum or anus
- Kidney dysfunction
- Children under 12 years (Senna containing medicines)
Caution while taking Dabur Laxirid
- Senna should not be used for longer than 1–2 weeks as frequent use causes the colon to function poorly, creating laxative dependence.
- Senna and Drug interactions
- Cardiac glycoside drugs.
- decrease the effects of hormone replacement therapy.
- warfarin, diuretics
- Birth control pills (Contraceptive drugs) reduced effect
Suggestions, Side-effects and Warnings of Dabur Laxirid
- It is completely safe to take this medicine in recommended doses occasionally.
- Do check the list of ingredients and their contraindications to avoid any side effects.
- Long-term, frequent use, or use of high doses has been linked to serious side effects including laxative dependence and liver damage.
- The laxative effect is seen 8–12 hours after administration, though sometimes up to 24 hours can be required.
- Sennosides irritate the lining of the large intestine, causing contraction.
- Senna containing medicines should not be used regularly.
- Senna should not be used by people with abdominal pain (either diagnosed or undiagnosed), intestinal blockage, Crohn’s disease, ulcerative colitis, appendicitis, stomach inflammation, anal prolapse, or hemorrhoids.
- Senna should not be used in people with dehydration, diarrhea, or loose stools. It can make these conditions worse.
- Senna intake along with diuretic might decrease potassium in the body.
- In some people, Senna can cause diarrhea. Diarrhea can increase the effects of warfarin and increase the risk of bleeding.
- If you take warfarin, do not take excessive amounts of senna.
- Elderly patients should initially take half of the normal prescribing dose.
- Senna can reduce the amount of estrone in the body.
- Senna may reduce the absorption of iron.
- Senna use should be avoided in children below the age of 12 years.
- Laxatives containing anthroquinone glycosides should not be used at a high dose for more than 2 weeks at a time due to the potential risk of causing an electrolyte imbalance.
- In rare cases, prolonged use of Senna may lead to cardiac arrhythmias, nephropathies, edema and accelerated bone deterioration.
- Senna abuse has also resulted in tetany, aspartyl glucosamine excretion and hypogammaglobulinemia.
- Long-term use of Senna may lead to loss of electrolytes, in particular potassium ions. As a result of hypokalemia, hyperaldosteronism, albuminuria, hematuria, inhibition of intestinal motility, and muscle weakness may occur. Enhancement of cardioactive glycosides and anti-arrythics may also occur with hypokalemia.
- Senna abuse has resulted in finger clubbing, which was reversible upon discontinuation of the drug.
- Anatomic alteration of the colon is seen secondary to chronic use with Senna (more than three times weekly for 1 year or longer). The result is a loss of haustral folds, a finding that suggests neuronal injury or damage to colonic longitudinal musculature.
- Prolonged use of Senna may lead to melanosis coli.
- Keep away from the sight and reach of children.
- Effectivity of herbal medicine depends on many factors. A medicine suitable for one person may not essentially give same result in another person.
- Exact dose depends on the age, strength, digestive power of the patient, the nature of the illness, the state of the viscera and humours, and the properties of individual drugs.
- Please maintain a gap of at least an hour between intake of any allopathic drug and Ayurvedic medicine to avoid drug interaction, if any.
- Do not use many different medicines for the treatments of same disease.
- Do not take during pregnancy without consulting doctor. If you’re pregnant or breastfeeding, try to ease constipation without taking a medicine by eating more fiber, drinking plenty of liquids and doing some gentle exercise.
- Laxatives are safe for pregnant women if they aren’t absorbed by the digestive system. Senna may not be suitable if you’re pregnant or breastfeeding because it is partly absorbed in gut. You may take Isabgol husk, a bulk forming laxative. Trivrit has abortifacient action.