ZENTEL Albendazole Dosage For Deworming

ZENTEL is a benzimidazole carbamate with anthelmintic and antiprotozoal activity against the intestinal and tissue parasites. This medicine is one of the most widely used Albendazole worldwide. This medicine come in form of tablet and suspension. Zentel is a trademark of the GlaxoSmithKline group of companies.

Zentel exhibits larvicidal, ovicidal and vermicidal activity, and exerts its antihelmintic effect by inhibiting tubulin polymerisation. This disrupts helminth metabolism, causing energy depletion, which immobilises and then kills the susceptible helminth.


Tablet containing 200 mg or 400 mg albendazole.

4% w/v suspension to be taken orally;4 g albendazole per 100 ml.

Uses of ZENTEL

It is used to treat following parasite worms:

Round-worm (Ascaris lumbricoides), pin-worm (Enterobius vermicularis), hook-worm (Necator americanus, Ancylostoma duodenale), whip-worm (Trichuris trichiura), thread-worm (Strongyloides stercoralis), tape-worm (Taenia spp and Hymenolepis nana only in the case of associated parasitism), Chlonorchiasis (Chlonorchis sinensis), Opisthorchiasis (Opisthorchis viverrini) and cutaneous larva migrans;Giardiasis (G.lamblia, G.duodenalis, G.intestinalis, Lamblia intestinalis) in children.






- Round-worm

- Pin-worm*

- Hook-worms

- Whip-worm

adults and children over 2 years of age

400 mg[two 200 mg tablet(s) or 10 ml 4% suspension]#

single dose (to be taken on an empty stomach)

children 1-2 years of age

200 mg (one 200 mg tablet or 5 ml 4% suspension)

single dose (to be taken on an empty stomach)

- Strongyloidiasis

- Taeniasis

- Hymenolepiasis**

adults and children over 2 years of age

400 mg (#see above)

one dose per day for 3 days (to be taken on an empty stomach)



adults and children over 2 years of age

400 mg (#see above)

two doses per day for 3 days (to be taken with food)

Cutaneous larva migrans

adults and

children over 2 years of age

400 mg

Once daily for 1 to 3 days (to be taken with food)

- Giardiasis

children 2 - 12

years of age only

400 mg (#see above)

one dose per day for 5 days (to be taken on an empty stomach)

*In order to obtain a complete cure in the case of pin-worm infestation, prescribe strict measures of hygiene, also treat the relatives and individuals sharing the same housing.

**In cases of proven Hymenolepiasis, retreatment in 10-21 days is recommended.

***Patients should be re-examined 1 month after treatment to confirm fluke eradication.

Direction to use

Some people, particularly young children, may experience difficulties swallowing the tablets whole and should be encouraged to chew the tablets with a little water;alternatively the tablets may be crushed.

Suspensions: Shake well before use

Do not use in following cases

ZENTEL should not be administered during pregnancy, or in women thought to be pregnant.

ZENTEL is contraindicated in patients with a known history of hypersensitivity to the drug (albendazole or constituents).

Warnings and precautions

In order to avoid administering ZENTEL during early pregnancy, women of childbearing age should initiate treatment during the first week of menstruation or after a negative pregnancy test.

Use with caution in elderly patients with evidence of hepatic dysfunction.

Patients with renal impairment should be carefully monitored.

Patients with abnormal liver function test results (transaminases) prior to commencing albendazole therapy should be carefully monitored.

Always take in recommended dosages.

Do Not use in Pregnancy and lactation

Albendazole should not be administered during pregnancy or in women thought to be pregnant (see Contraindications).

It is not known whether albendazole or its metabolites are secreted in human breast milk. Thus ZENTEL should not be used during lactation unless the potential benefits are considered to outweigh the potential risks associated with treatment.


Hypersensitivity reactions including rash, pruritis and urticaria (rare).

Headache and dizziness (uncommon).

Upper gastrointestinal symptoms (e.g. epigastric or abdominal pain, nausea, vomiting) and diarrhoea (uncommon).

Elevations of hepatic enzymes (rare).

Erythema multiforme, Stevens-Johnson syndrome (very rare).

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