Silverex ointment is a broad spectrum anti-microbial cream containing Silver sulfadiazine. Silver sulfadiazine has broad antimicrobial activity. It is active against gram-positive,gram-negative bacteria,some yeasts and fungi. The silver salt acts mainly on the cell wall and membrane to disrupt its integrity thus allowing it to impair the essential enzymes,bacterial DNA and RNA leading to cell death.
Silver sulfadiazine slowly releases sulfadiazine and up to 10% of sulfadiazine may be absorbed by body. Therefore it is contraindicated in many conditions. Silverex ointment is applied for treating and prevention of infection in severe burns.
Compostion of Silverex cream
Silver sulphadiazine 1% w/w,chlorhexidine gluconate 0.2% w/w
Uses of Silverex Cream
- Superficial bacterial infections
- Herpes zoster,post-operative prophylaxis
- Bed sores and ulcers
The cream is a topical antibiotic and used in the treatment of dermatological diseases. It should be applied on affected area one to two times a day.
The cream in contraindicated in hypersensitivity to sulphonamides,premature infants and infants below age of 2 month,pregnancy and breastfeeding.